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Canisius is easily accessible by public transportation. Bus service is available from the following school districts at no additional cost:

Amherst, Buffalo, Cheektowaga, Cheektowaga/Sloan, Clarence, Cleveland Hill, Depew, Frontier, Grand Island, Hamburg, Iroquois, Kenmore-Tonawanda, Lackawanna, Lancaster, Maryvale, Niagara-Wheatfield, North Tonawanda, Orchard Park, Starpoint, Sweet Home, West Seneca and Williamsville

Canisius also partners with families to provide private bus transportation from the following areas: East Aurora, Lewiston, Lockport and Niagara Falls